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1,1'-Oxydi-2-propano CAS：110-98-5

Highly Efficient Solvent: Capable of smoothly dissolving water, oils and hydrocarbons, making it widely applicable in fragrances and cosmetic preparations.

Faint Aroma Profile: Almost odorless, which renders it particularly ideal for sensitive formulations like perfumes and skin care products.

Low Toxicity & Skin Compatibility: Features very low skin irritation and weak systemic toxicity, guaranteeing safe use in external skin applications.

Powerful Hydrating Agent: Acts as both a coupling agent and a moisturizing component, boosting the overall performance of various cosmetic formulas.

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Product Details

1. Product Overview

1,1'-Oxydi-2-propanol, better known as Dipropylene Glycol (DPG), is a colorless, low-viscosity, nearly odorless liquid classified under the glycol ether family. With a molecular formula of C₆H₁₄O₃ and CAS registry number 110-98-5, it features two hydroxyl (-OH) groups and an ether bond, making it a flexible diol with strong solvent capabilities.

It also goes by several other chemical names, including bis(2-hydroxypropyl) ether, 1,1'-oxybis-2-propanol, 4-oxaheptane-2,6-diol, and 1-(2-hydroxypropoxy)propan-2-ol, and has a molecular weight of 134.17 g/mol. Due to two chiral centers in its structure, DPG exists as a mixture of isomers, leading to undefined stereochemistry. It is hygroscopic and fully miscible with water and numerous organic solvents. Its favorable toxicology profile—minimal skin irritation and very low systemic toxicity—has led to its wide adoption in cosmetics, fragrances, industrial resins, and plasticizers.

1,1'-Oxydi-2-propano CAS：110-98-5

2. Key Features

Strong Solvency Performance: Shows excellent dissolving power for a wide range of substances, such as cellulose acetate, nitrocellulose, shellac, castor oil, and various resins, making it a top choice as a solvent and coupling agent.
Gentle Scent & Skin-Friendly: Almost completely odorless, with very low skin irritation and toxicity, making it ideal for sensitive applications in perfumes, cosmetics, and personal care items.
Full Compatibility with Solvents: Mixes freely with water, methanol, ether, toluene, and many hydrocarbons, offering great flexibility for formulating both water-based and non-aqueous products.
Hygroscopic & Moisturizing Effects: Absorbs and retains moisture from the air efficiently, acting as an effective humectant and moisturizer in cosmetic and personal care formulas.
Stable Chemical Properties: Remains stable under normal storage conditions, with a high boiling point (232.8 °C) and flash point (137.7 °C / 280 °F), lowering fire risks during production and storage.
Cross-Industry Versatility: Serves multiple roles across industries: solvent in coatings and inks, coupling agent in cleaning products, humectant in cosmetics, intermediate in resin production, and plasticizer in polymer materials.
Superior Weather Resistance: When used in unsaturated polyester and alkyd resins, it enhances the finished product’s flexibility, crack resistance, and long-term resistance to yellowing.

3. Technical Specifications with Explanations

Parameter	Typical Value	Description & Significance
Molecular Formula	C₆H₁₄O₃	Diol structure with ether linkage; two hydroxyl groups provide reactivity and hydrogen bonding capacity .
Molecular Weight	134.17 g/mol	Used for stoichiometric calculations in polymer synthesis and formulation .
CAS Number	110-98-5	Primary chemical registry identifier .
EINECS Number	203-821-4	European inventory identifier .
Appearance	Colorless, slightly viscous liquid	Visual quality indicator; should be clear and free from suspended matter .
Odor	Nearly odorless	Critical for fragrance and cosmetic applications where product scent must not be masked .
Purity	≥99.0% – 99.9% (Industrial/Grade)	Core specification. Higher purity minimizes impurities that could affect polymerization or cause discoloration in end products .
Water Content (Moisture)	≤0.05% – 0.2%	Critical quality parameter. Low moisture ensures stability in moisture-sensitive applications (polyurethane systems, electronics) .
Boiling Point	232.8 °C (760 mmHg)	High boiling point enables use in high-temperature processes and reduces evaporation losses during handling .
Boiling Point	229–233 °C range reported
Melting Point	< -40 °C	Remains liquid even in extremely cold environments, facilitating storage and handling without heating requirements .
Flash Point	137.7 °C (open cup)	High flash point indicates low fire risk during storage, transport, and processing .
Flash Point	138 °C reported
Density	1.0252 g/mL at 20°C/20°C	Slightly heavier than water; used for volume-to-weight conversions and formulation calculations .
Density	Approximately 8.5 lb/gal
Vapor Pressure	0.03 mm Hg at 25°C	Very low volatility reduces worker inhalation exposure and evaporative losses .
Vapor Density	4.63 (Air = 1)	Heavier than air; vapors may accumulate in low-lying areas .
Viscosity	1.07 cP at 20°C	Low viscosity facilitates pumping, mixing, and spray applications .
Solubility	Water solubility: ~100 g/L (miscible in all proportions)	Complete water miscibility and broad organic solubility enable formulation in diverse systems .
Solubility	Organic solvents: Miscible with methanol, ethanol, ether, toluene, acetone
Refractive Index	1.439 at 25°C	Optical property used for quality control and purity verification .
Acidity	≤0.02% (as acetic acid)	Low acidity prevents corrosion and unwanted side reactions in sensitive applications .
Sulfate Content	≤0.01% (none detected in high purity grades)	Indicates purity from sulfonation byproducts .
Residue on Ignition	≤0.007%	Measures non-volatile inorganic impurities .
Color (APHA)	≤5 (Platinum-Cobalt scale)	Extremely low color value essential for clear, colorless end products (cosmetics, coatings) .
Coefficient of Expansion	0.00073/K at 20°C	Used for volume correction at different temperatures during bulk storage and transport .

4. Applications

Cosmetics & Personal Care

Fragrance Solvent & Carrier — The most widely used solvent in perfumery (>50% of fine fragrances) due to its nearly odorless nature, excellent co-solvency with essential oils, and skin-friendly profile .
Skin Care Products — Functions as humectant and moisturizer in face creams, hand lotions, body washes, shower gels, and lip balms (typically ≤10% formulation) .
Hair Care — Used in conditioners, styling products, and hair treatments for moisturizing properties .
Deodorants & Antiperspirants — Serves as solvent and coupling agent in clear gel formulations .
Cold Creams & Cleansers — Provides emollient properties and enhances spreadability .

Paints, Coatings & Inks

Solvent for Cellulosic Polymers — Excellent solvent for cellulose acetate, nitrocellulose, and shellac in lacquers, wood coatings, and printing inks .
Coalescing Agent — Aids film formation in water-based architectural and industrial coatings.
Paint Removers — Component in stripper formulations due to high solvency.
Dyes & Pigments — Solvent and dispersant in dye and pigment preparations .

Plastics & Resin Synthesis

Unsaturated Polyester Resins (UPR) — Used in resin production, imparting superior flexibility, crack resistance, and weather resistance to finished composites (boats, automotive parts, construction panels) .
Alkyd Resins — Modifier in alkyd coatings for improved flexibility and durability .
Polyurethane Systems — Reactive diluent and chain extender in PU elastomers, foams, and adhesives.
Plasticizers — Intermediate in plasticizer production for flexible PVC and other polymers .

Industrial & Specialty Chemicals

Hydraulic Brake Fluids — Component in DOT 3 and DOT 4 brake fluids due to high boiling point and water compatibility .
Cutting Fluids & Metalworking Lubricants — Provides cooling, lubrication, and corrosion inhibition .
Extracting Agent — Used in liquid-liquid extraction processes for aromatic hydrocarbons .
Fumigants — Component in agricultural fumigant formulations .
Synthetic Detergents — Intermediate in surfactant production .

Household & Industrial Cleaning

Coupling Agent — Enhances compatibility between water and organic phases in all-purpose cleaners, degreasers, and hard surface cleaners.
Paint Strippers — Component in industrial and consumer-grade remover formulations.

Fragrance & Flavor Industry

Fixative — Slows evaporation rate of volatile fragrance notes, extending scent longevity.
Diluent — Safe, odorless carrier for concentrated fragrance oils.

5. Purchasing & Selection Guide

Select by Application & Quality Requirements

·Industrial Grade (≥99.0%) — Recommended for:

Unsaturated polyester and alkyd resin manufacturing
Industrial solvent applications
Plasticizer production
Applications where slight odor and color are acceptable

Technical Grade (≥99.0%, tighter specs) — Suitable for:

Paints, coatings, and printing inks
Industrial and household cleaners
Hydraulic brake fluids
Metalworking fluids

High Purity Grade (≥99.5–99.9%, low odor/color) — Essential for:

Fine fragrances and perfumery — Must be nearly odorless to avoid altering scent profiles
Cosmetics and personal care products — Face creams, lotions, body washes, lip care
Pharmaceutical intermediates
Premium consumer products requiring exceptional purity

USP Grade — Required for:

Pharmaceutical excipients
Food contact applications
Applications requiring pharmacopoeia compliance

Packaging & Logistics Considerations

Standard Packaging: 215 kg (approximately 475 lb) steel drums
Bulk Options: 1000 kg IBC totes, 17.2–20 MT ISO tanks, flexitanks
Special Handling: High purity grades may require nitrogen blanketing and moisture-proof packaging
Storage: Store in tightly sealed containers in cool, dry, well-ventilated area away from direct sunlight and oxidizing agents
Shelf Life: Minimum 24 months when stored properly

Regulatory & Compliance Considerations

Verify applicable regulations: REACH (EU), TSCA (US), IECSC (China), etc.
Cosmetic grades should comply with regional cosmetic ingredient standards (EU Cosmetic Regulation, FDA, China Cosmetics Supervision and Administration Regulation)
USP grade required for pharmaceutical and certain food contact applications
Not classified as hazardous for transport (non-DG) under most regulations

1,1'-Oxydi-2-propano CAS：110-98-5