Idebenone CAS：58186-27-9
Solubility and Stability： Traits This substance is lipophilic, showing good solubility in DMSO and many organic solvents, yet it does not dissolve in water. Under recommended low-temperature storage, it can stay chemically stable for up to one year.
Physicochemical Properties： Idebenone appears as an orange crystalline solid with a relatively low melting point. It dissolves easily in many organic solvents but hardly dissolves in water at all.
Therapeutic and Cosmetic Uses： It is widely used in pharmaceutical preparations due to its antioxidant effects and ability to regulate mitochondrial activity, and is increasingly applied in treating neurodegenerative disorders. It is also added to cosmetics for skin protection and anti-aging purposes.
Safety and Handling Guidelines： Labeled as a Category Xi irritant, this product requires careful handling to avoid skin and eye contact. Suitable protective gear must be worn during laboratory and industrial operations.
Idebenone appears as a yellow crystalline or powdery substance with no obvious odor. It is almost insoluble in water, but dissolves easily in chloroform, methanol, and absolute ethanol. It is soluble in ethyl acetate, yet cannot be dissolved in n‑hexane.
| Melting point | 52-550C |
| Boiling point | 497.3±45.0 °C(Predicted) |
| density | 1.08±0.1 g/cm3(Predicted) |
| storage temp. | room temp |
| solubility | Soluble in DMSO (up to 25 mg/ml). |
| form | Solid |
| pka | 15.20±0.10(Predicted) |
| color | Orange |
| Merck | 144,888 |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| InChI | InChI=1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3 |
| InChIKey | JGPMMRGNQUBGND-UHFFFAOYSA-N |
| SMILES | C1(=O)C(OC)=C(OC)C(=O)C(C)=C1CCCCCCCCCCO |
| LogP | 3.490 (est) |
| CAS DataBase Reference | 58186-27-9(CAS DataBase Reference) |
| Hazard Codes | Xi |
| WGK Germany | 3 |
| RTECS | GU5290000 |
| HS Code | 2933399990 |
